A model for PUMA-mediated apoptosis. PUMA activates Bax/Bak indirectly... | Download Scientific Diagram
The BCL-2 protein family, BH3-mimetics and cancer therapy | Cell Death & Differentiation
Cooperation of BH3-only proteins in killing neurons
Basal Patologi KU - BAD, BID and PUMA proteins shift the balance between the pro-apoptotic and anti-apoptotic family members by neutralizing the actions of anti-apoptotic proteins like BCL2 and BCL-XL, thereby promoting
Efficacy and specificity of inhibitors of BCL-2 family protein interactions assessed by affinity measurements in live cells | Science Advances
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?: Trends in Cell Biology
Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance - ScienceDirect
BCL-2
PROTACs are effective in addressing the platelet toxicity associated with BCL-XL inhibitors
Frontiers | Targeting the Bcl-2 Family in B Cell Lymphoma
Multimodal Interaction with BCL-2 Family Proteins Underlies the Proapoptotic Activity of PUMA BH3 - ScienceDirect
Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins | PNAS
Interplay of Bcl-2 Proteins Decides the Life or Death Fate
BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis | PLOS Pathogens
BCL-2 family: integrating stress responses at the ER to control cell demise | Cell Death & Differentiation
Dysregulation of BCL-2 family proteins by leukemia fusion genes - ScienceDirect
Why do BCL-2 inhibitors work and where should we use them in the clinic? | Cell Death & Differentiation
BCL‐2‐family protein tBID can act as a BAX‐like effector of apoptosis | The EMBO Journal
PUMA-mediated apoptosis. PUMA is induced by a wide range of death... | Download Scientific Diagram
A) Bcl-2 family member effector proteins (Bax and Bak) oligomerize and... | Download Scientific Diagram
PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis | Nature Chemical Biology
A review of the role of Puma, Noxa and Bim in the tumorigenesis, therapy and drug resistance of chronic lymphocytic leukemia | Cancer Gene Therapy
Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment - ScienceDirect
Life | Free Full-Text | BH3-Only Proteins Noxa and Puma Are Key Regulators of Induced Apoptosis
